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KPTI

Karyopharm Therapeutics Inc.

0.00 (0.00%)前一交易日收盤 2026-09-17
美股 · Nasdaq · 生技醫療 · Pharmaceutical Preparations
1.70USD424K成交股數38.6M市值本益比(近四季)0.3股價營收比-11.9%營收年增(近四季)2026-11-03下次財報

內部人交易 SEC Form 4 · 董事、高階主管與持股 10% 以上股東 · 交易後兩個營業日內申報

買賣點與股價近一年

2026-09-01 Abate Kristin(Chief Accounting Officer) 賣出 19 股 @ 2.02 ≈ 38.382026-07-28 Poulton Stuart(EVP, Chief Development Officer) 賣出 189 股 @ 7.10 ≈ 1K2026-05-14 Abate Kristin(Chief Accounting Officer) 賣出 53 股 @ 9.50 ≈ 503.502026-05-14 Paulson Richard A.(President and CEO) 賣出 2.2K 股 @ 9.50 ≈ 21K2026-05-14 Poulton Stuart(EVP, Chief Development Officer) 賣出 403 股 @ 9.50 ≈ 4K2026-05-14 Rangwala Reshma(EVP & Chief Medical Officer) 賣出 408 股 @ 9.50 ≈ 4K2026-05-14 Cheng Sohanya Roshan(EVP & Chief Commercial Officer) 賣出 324 股 @ 9.50 ≈ 3K2026-05-14 Mano Michael(EVP, CLO&Secretary) 賣出 266 股 @ 9.50 ≈ 3K2026-04-21 Rangwala Reshma(EVP & Chief Medical Officer) 賣出 449 股 @ 8.94 ≈ 4K2026-03-02 Paulson Richard A.(President and CEO) 賣出 12.4K 股 @ 9.41 ≈ 116K2026-03-02 Abate Kristin(Chief Accounting Officer) 賣出 559 股 @ 9.41 ≈ 5K2026-03-02 Poulton Stuart(EVP, Chief Development Officer) 賣出 5.1K 股 @ 9.41 ≈ 48K2026-03-02 Mano Michael(EVP, CLO&Secretary) 賣出 3.5K 股 @ 9.41 ≈ 33K2026-03-02 Cheng Sohanya Roshan(EVP & Chief Commercial Officer) 賣出 4.6K 股 @ 9.41 ≈ 43K2026-03-02 Rangwala Reshma(EVP & Chief Medical Officer) 賣出 5.1K 股 @ 9.41 ≈ 48K2026-02-17 Poulton Stuart(EVP, Chief Development Officer) 賣出 378 股 @ 8.63 ≈ 3K2026-02-03 Macomber Lori(EVP, CFO & Treasurer) 賣出 1.6K 股 @ 6.30 ≈ 10K2026-01-28 Abate Kristin(Chief Accounting Officer) 賣出 50 股 @ 7.03 ≈ 351.502026-01-21 Abate Kristin(Chief Accounting Officer) 賣出 265 股 @ 5.96 ≈ 2K2025-10-01 Abate Kristin(Chief Accounting Officer) 賣出 362 股 @ 6.30 ≈ 2K10.991.242025-092026-09

公開市場買進 · 公開市場賣出 · 空心 = 10b5-1 預設計畫(事先排程,不代表當下看法)。近一年,只畫 P / S 兩種代碼。

統計

近 90 天 買進筆數 · 金額 · 人數0 · 0.00 · 0
近 90 天 賣出筆數 · 金額 · 人數2 · 1K · 2
其中 10b5-1 計畫賣出0
近 180 天 買進 · 賣出金額0.00 · 40K
近 180 天 淨額−40K

公開市場買進(P)是內部人自掏腰包,通常比賣出更有資訊含量 —— 賣出的理由很多(繳稅、分散、買房),買進的理由只有一個。

10b5-1 是事先排定的交易計畫,執行時點不反映當下看法。獲配股票(A)、繳稅扣股(F)、選擇權執行(M)是薪酬流程,不是意見。

交易日申報日申報人職稱代碼股數價格金額交易後持股原件
2026-09-0109-02Abate KristinChief Accounting OfficerS 公開市場賣出192.0238.3823.8KSEC
2026-07-2807-30Poulton StuartEVP, Chief Development OfficerS 公開市場賣出1897.101K94.6KSEC
2026-05-2105-26Greene Barry EDirectorA 獲配股票15.5K16.4KSEC
2026-05-2105-26BOHLIN GAREN GDirectorA 獲配股票15.5K18.5KSEC
2026-05-2105-26Schor ChenDirectorA 獲配股票15.5K15.5KSEC
2026-05-2105-26PAKIANATHAN DEEPIKADirectorA 獲配股票15.5K15.5KSEC
2026-05-2105-26Oliger Christy J.DirectorA 獲配股票15.5K15.5KSEC
2026-05-2105-26Su ZhenDirectorA 獲配股票15.5K15.5KSEC
2026-05-1405-15Abate KristinChief Accounting OfficerS 公開市場賣出539.50503.5023.8KSEC
2026-05-1405-15Paulson Richard A.President and CEOS 公開市場賣出2.2K9.5021K270KSEC
2026-05-1405-15Poulton StuartEVP, Chief Development OfficerS 公開市場賣出4039.504K94.8KSEC
2026-05-1405-15Rangwala ReshmaEVP & Chief Medical OfficerS 公開市場賣出4089.504K56.8KSEC
2026-05-1405-15Cheng Sohanya RoshanEVP & Chief Commercial OfficerS 公開市場賣出3249.503K108KSEC
2026-05-1405-15Mano MichaelEVP, CLO&SecretaryS 公開市場賣出2669.503K94.4KSEC
2026-05-1305-15Cheng Sohanya RoshanEVP & Chief Commercial OfficerA 獲配股票947108KSEC
2026-05-1305-15Abate KristinChief Accounting OfficerA 獲配股票12123.9KSEC
2026-05-1305-15Mano MichaelEVP, CLO&SecretaryA 獲配股票70094.7KSEC
2026-05-1305-15Paulson Richard A.President and CEOA 獲配股票4.9K272KSEC
2026-05-1305-15Poulton StuartEVP, Chief Development OfficerA 獲配股票89695.2KSEC
2026-05-1305-15Rangwala ReshmaEVP & Chief Medical OfficerA 獲配股票94757.2KSEC
2026-04-2104-22Rangwala ReshmaEVP & Chief Medical OfficerS 公開市場賣出4498.944K56.3KSEC
2026-03-0203-03Paulson Richard A.President and CEOS 公開市場賣出12.4K9.41116K267KSEC
2026-03-0203-03Abate KristinChief Accounting OfficerS 公開市場賣出5599.415K22.1KSEC
2026-03-0203-03Poulton StuartEVP, Chief Development OfficerS 公開市場賣出5.1K9.4148K94.3KSEC
2026-03-0203-03Mano MichaelEVP, CLO&SecretaryS 公開市場賣出3.5K9.4133K94.0KSEC
2026-03-0203-03Cheng Sohanya RoshanEVP & Chief Commercial OfficerS 公開市場賣出4.6K9.4143K107KSEC
2026-03-0203-03Rangwala ReshmaEVP & Chief Medical OfficerS 公開市場賣出5.1K9.4148K56.7KSEC
2026-02-1702-19Poulton StuartEVP, Chief Development OfficerS 公開市場賣出3788.633K99.4KSEC
2026-02-0502-09Paulson Richard A.President and CEOA 獲配股票81.1K279KSEC
2026-02-0302-04Macomber LoriEVP, CFO & TreasurerS 公開市場賣出1.6K6.3010K85.1KSEC
2026-01-3102-03Poulton StuartEVP, Chief Development OfficerA 獲配股票32.4K99.8KSEC
2026-01-3102-03Mano MichaelEVP, CLO&SecretaryA 獲配股票32.4K97.5KSEC
2026-01-3102-03Macomber LoriEVP, CFO & TreasurerA 獲配股票32.4K86.7KSEC
2026-01-3102-03Cheng Sohanya RoshanEVP & Chief Commercial OfficerA 獲配股票32.4K112KSEC
2026-01-3102-03Rangwala ReshmaEVP & Chief Medical OfficerA 獲配股票32.4K61.8KSEC
2026-01-2801-29Abate KristinChief Accounting OfficerS 公開市場賣出507.03351.5022.6KSEC
2026-01-2701-29Abate KristinChief Accounting OfficerA 獲配股票9222.7KSEC
2026-01-2101-22Abate KristinChief Accounting OfficerS 公開市場賣出2655.962K22.6KSEC
2025-10-1510-16Paulson Richard A.President and CEOA 獲配股票114K198KSEC
2025-10-1510-16Cheng Sohanya RoshanEVP & Chief Commercial OfficerA 獲配股票43.6K79.5KSEC
2025-10-1510-16Abate KristinChief Accounting OfficerA 獲配股票12.8K22.8KSEC
2025-10-1510-16Macomber LoriEVP, CFO & TreasurerA 獲配股票43.6K54.3KSEC
2025-10-1510-16Poulton StuartEVP, Chief Development OfficerA 獲配股票39.7K67.4KSEC
2025-10-1510-16Mano MichaelSVP, General Counsel&SecretaryA 獲配股票43.6K65.1KSEC
2025-10-0110-03Abate KristinChief Accounting OfficerS 公開市場賣出3626.302K10.0KSEC
2025-09-1509-16Paulson Richard A.President and CEOS 公開市場賣出1.3K6.438K84.0KSEC
2025-09-1509-16Mano MichaelSVP, General Counsel&SecretaryS 公開市場賣出2346.432K21.4KSEC
2025-09-1509-16Poulton StuartEVP, Chief Development OfficerS 公開市場賣出4016.433K27.7KSEC
2025-09-1509-16Rangwala ReshmaEVP & Chief Medical OfficerS 公開市場賣出4086.433K29.4KSEC
2025-09-1509-16Cheng Sohanya RoshanEVP & Chief Commercial OfficerS 公開市場賣出3256.432K35.9KSEC
2025-09-1509-16Abate KristinChief Accounting OfficerS 公開市場賣出236.43147.8910.4KSEC
2025-09-1209-16Abate KristinChief Accounting OfficerA 獲配股票4610.4KSEC
2025-09-1209-16Paulson Richard A.President and CEOA 獲配股票2.8K85.3KSEC
2025-09-1209-16Cheng Sohanya RoshanEVP & Chief Commercial OfficerA 獲配股票94536.2KSEC
2025-09-1209-16Mano MichaelSVP, General Counsel&SecretaryA 獲配股票61221.7KSEC
2025-09-1209-16Poulton StuartEVP, Chief Development OfficerA 獲配股票88828.1KSEC
2025-09-1209-16Rangwala ReshmaEVP & Chief Medical OfficerA 獲配股票94529.8KSEC
2025-09-0309-04Abate KristinChief Accounting OfficerS 公開市場賣出126.7881.369.5KSEC
2025-07-2907-30Poulton StuartEVP, Chief Development OfficerS 公開市場賣出1914.37834.6727.2KSEC
2025-07-2207-23Abate KristinChief Accounting OfficerS 公開市場賣出2384.00952.009.5KSEC
2025-05-0605-07Paulson Richard A.President and CEOS 公開市場賣出2367.122K82.5KSEC
2025-04-2304-24Rangwala ReshmaEVP & Chief Medical OfficerS 公開市場賣出4196.173K28.9KSEC
2025-04-0404-07Paulson Richard A.President and CEOS 公開市場賣出2453.74916.3082.7KSEC
2025-03-0403-06Mano MichaelSVP, General Counsel&SecretaryS 公開市場賣出2.8K6.2918K21.0KSEC
2025-03-0403-06Rangwala ReshmaEVP & Chief Medical OfficerS 公開市場賣出3.6K6.2923K29.3KSEC
2025-03-0403-06Cheng Sohanya RoshanEVP & Chief Commercial OfficerS 公開市場賣出3.4K6.2922K34.3KSEC
2025-03-0403-06Poulton StuartEVP, Chief Development OfficerS 公開市場賣出3.5K6.2922K27.4KSEC
2025-03-0403-06Abate KristinChief Accounting OfficerS 公開市場賣出5716.294K9.7KSEC
2025-03-0403-06Paulson Richard A.President and CEOS 公開市場賣出11.7K6.2974K83.0KSEC
2025-02-2803-04Mano MichaelSVP, General Counsel&SecretaryA 獲配股票2.3K23.8KSEC
2025-02-2803-04Cheng Sohanya RoshanEVP & Chief Commercial OfficerA 獲配股票5.4K33.2KSEC
2025-02-2803-04Rangwala ReshmaEVP & Chief Medical OfficerA 獲配股票4.6K32.9KSEC
2025-02-2803-04Rangwala ReshmaEVP & Chief Medical OfficerA 獲配股票5.4K28.3KSEC
2025-02-2803-04Poulton StuartEVP, Chief Development OfficerA 獲配股票4.6K31.0KSEC
2025-02-2803-04Poulton StuartEVP, Chief Development OfficerA 獲配股票5.0K26.4KSEC
2025-02-2803-04Abate KristinChief Accounting OfficerA 獲配股票93310.3KSEC
2025-02-2803-04Paulson Richard A.President and CEOA 獲配股票20.0K94.7KSEC
2025-02-2803-04Cheng Sohanya RoshanEVP & Chief Commercial OfficerA 獲配股票4.6K37.8KSEC
2025-02-2803-04Mano MichaelSVP, General Counsel&SecretaryA 獲配股票3.3K21.6KSEC
2025-02-1802-19Poulton StuartEVP, Chief Development OfficerS 公開市場賣出5.9K0.634K321KSEC

機構持股(13F) 管理規模 1 億美元以上的機構,每季末後 45 天內申報 · 最新 2026-06-30

前 25 大持有機構季末市值 · 與前一季股數比較

機構持股季末市值股數季變化動作
RA CAPITAL MANAGEMENT, L.P.1.9M18.7M新進新進
ADAGE CAPITAL PARTNERS GP, L.L.C.1.5M14.9M新進新進
ACORN CAPITAL ADVISORS, LLC1.5M14.8M新進新進
GOLDMAN SACHS GROUP INC1.4M13.9M新進新進
BlackRock, Inc.1.4M13.9M新進新進
Kalehua Capital Management LLC1.4M13.4M新進新進
VANGUARD CAPITAL MANAGEMENT LLC959K9.4M新進新進
Catalio Capital Management, LP941K9.2M新進新進
Avidity Partners Management LP924K9.0M新進新進
Two Sigma TWO SIGMA INVESTMENTS, LP695K6.8M新進新進
NEA Management Company, LLC577K5.6M新進新進
GEODE CAPITAL MANAGEMENT, LLC531K5.2M新進新進
Ghisallo Capital Management LLC500K4.9M新進新進
Soleus Capital Management, L.P.440K4.3M新進新進
UBS Group AG354K3.5M新進新進
STATE STREET CORP326K3.2M新進新進
Affinity Asset Advisors, LLC313K3.1M新進新進
Brevan Howard Capital Management LP310K3.0M新進新進
千禧 MILLENNIUM MANAGEMENT LLC306K3.0M新進新進
Boxer Capital Management, LLC303K3.0M新進新進
Davidson Kempner Capital Management LP300K2.9M新進新進
SILVERARC CAPITAL MANAGEMENT, LLC297K2.9M新進新進
Eversept Partners, LP276K2.7M新進新進
JPMORGAN CHASE & CO208K2.1M新進新進
MORGAN STANLEY203K2.0M新進新進

持有機構數近 12 季

2025-03-31 持有機構 4 家 · 合計 16.8K 股20252025-06-30 持有機構 3 家 · 合計 13.1K 股2025-09-30 持有機構 51 家 · 合計 2.9M 股2025-12-31 持有機構 69 家 · 合計 10.1M 股2026-03-31 持有機構 76 家 · 合計 18.0M 股20262026-06-30 持有機構 96 家 · 合計 21.8M 股963

每季 13F 申報中持有本股的機構家數;綠柱 = 比上季少。機構數是「有多少人在船上」,不是「買了多少」。

持有機構 · 季變化96 +20
新進 / 出清 / 加碼 / 減碼96 / 0 / 0 / 0
機構合計持股 · 佔流通股21.8M · 96.1%
合計季末市值201M

13F 只申報多頭部位(含可轉債與選擇權,選擇權這裡已排除),不申報放空,也不申報 1 億美元以下的機構。同一集團多個申報主體會各算一家。

放空餘額 FINRA 每月兩次(15 日與月底結算)· 最新 2026-08-31

空單佔流通股近 13 個月

2025-08-15 空單 2.1M 股 · 佔流通 9.45% · 回補 7.9 天2025-08-29 空單 2.2M 股 · 佔流通 9.62% · 回補 15.6 天2025-09-15 空單 2.2M 股 · 佔流通 9.72% · 回補 30.2 天2025-09-30 空單 2.3M 股 · 佔流通 9.95% · 回補 19.6 天2025-10-15 空單 1.4M 股 · 佔流通 6.34% · 回補 3.3 天2025-10-31 空單 648K 股 · 佔流通 2.86% · 回補 4.7 天2025-11-14 空單 716K 股 · 佔流通 3.16% · 回補 7.3 天2025-11-28 空單 341K 股 · 佔流通 1.51% · 回補 3.0 天2025-12-15 空單 299K 股 · 佔流通 1.32% · 回補 1.3 天2025-12-31 空單 354K 股 · 佔流通 1.56% · 回補 1.3 天2026-01-15 空單 744K 股 · 佔流通 3.28% · 回補 1.5 天2026-01-30 空單 1.4M 股 · 佔流通 5.96% · 回補 4.0 天2026-02-13 空單 2.5M 股 · 佔流通 10.87% · 回補 2.9 天2026-02-27 空單 3.0M 股 · 佔流通 13.10% · 回補 5.8 天2026-03-13 空單 3.6M 股 · 佔流通 15.84% · 回補 5.0 天2026-03-31 空單 5.5M 股 · 佔流通 24.06% · 回補 2.3 天2026-04-15 空單 5.7M 股 · 佔流通 25.21% · 回補 9.0 天2026-04-30 空單 5.3M 股 · 佔流通 23.34% · 回補 14.5 天2026-05-15 空單 5.3M 股 · 佔流通 23.26% · 回補 11.5 天2026-05-29 空單 5.3M 股 · 佔流通 23.58% · 回補 11.9 天2026-06-15 空單 5.6M 股 · 佔流通 24.62% · 回補 16.8 天2026-06-30 空單 6.6M 股 · 佔流通 29.03% · 回補 9.1 天2026-07-15 空單 6.3M 股 · 佔流通 27.83% · 回補 17.1 天2026-07-31 空單 7.6M 股 · 佔流通 33.31% · 回補 2.7 天2026-08-14 空單 9.6M 股 · 佔流通 42.51% · 回補 4.5 天2026-08-31 空單 9.8M 股 · 佔流通 43.27% · 回補 9.3 天43.3%0%2025-082026-08

FINRA 每月兩次結算的空單餘額佔流通股數的比例,近 13 個月。滑到柱子看股數與回補天數。

最新一期

空單股數9.8M
與上期比+1.8%
佔流通股數43.27%
日均成交量1.0M
回補天數9.4

空單佔比 10% 以上算高、20% 以上算很高(這是通行的說法,不是本站的判斷)。回補天數 = 空單 ÷ 日均量,天數愈長,空方要出場時愈容易推升股價。

放空餘額是「有人借股票賣掉還沒還」的存量,不代表看空的人正在加碼;避險基金做多空配對時也會產生空單。

結算日空單股數與上期比佔流通股日均量回補天數
2026-08-319.8M+1.8%43.27%1.0M9.4
2026-08-149.6M+27.6%42.51%2.2M4.5
2026-07-317.6M+19.7%33.31%2.8M2.7
2026-07-156.3M-4.1%27.83%369K17.1
2026-06-306.6M+17.9%29.03%722K9.1
2026-06-155.6M+4.4%24.62%333K16.8
2026-05-295.3M+1.4%23.58%449K11.9
2026-05-155.3M-0.3%23.26%458K11.5
2026-04-305.3M-7.4%23.34%365K14.5
2026-04-155.7M+4.8%25.21%636K9.0
2026-03-315.5M+51.9%24.06%2.4M2.3
2026-03-133.6M+20.9%15.84%714K5.0
2026-02-273.0M+20.5%13.10%516K5.8
2026-02-132.5M+82.5%10.87%854K2.9
2026-01-301.4M+81.7%5.96%342K4.0
2026-01-15744K+110.2%3.28%504K1.5
2025-12-31354K+18.3%1.56%279K1.3
2025-12-15299K-12.3%1.32%225K1.3
2025-11-28341K-52.4%1.51%114K3.0
2025-11-14716K+10.5%3.16%97.7K7.3
2025-10-31648K-54.9%2.86%138K4.7
2025-10-151.4M-36.2%6.34%434K3.3
2025-09-302.3M+2.4%9.95%115K19.6
2025-09-152.2M+1.0%9.72%73.0K30.2
2025-08-292.2M+1.7%9.62%140K15.6
2025-08-152.1M+0.8%9.45%271K7.9